CJC-1295 No DAC (10mg)

CJC-1295 No DAC, also widely known as Modified GRF 1-29, is a 29-amino-acid tetrasubstituted peptide derivative corresponding to the functional core of endogenous GHRH. Designed without the Drug Affinity Complex (DAC) reactive group, this variant offers a shorter, more natural half-life profile that mimics physiological, short-acting GHRH pulses in laboratory modeling. In research environments, CJC-1295 No DAC is extensively studied for its ability to bind selectively to pituitary GHRH receptors, stimulating pulsatile growth hormone secretion and downstream IGF-1 expression. True Lab Peptides supplies CJC-1295 No DAC at an independently verified purity threshold of $\ge$99%, providing qualified researchers with a dependable standard for high-precision analytical studies.

Key Research Applications

• Pulsatile GHRH Receptor Signaling: Engineered to investigate short-acting pituitary somatotroph activation and physiological growth hormone pulse kinetics.

• Neuroendocrine Pathway Research: Ideal for examining feedback mechanisms within the hypothalamic-pituitary-somatotropic axis without long-term receptor saturation.

• Tissue Response & Cellular Longevity: Utilized in studying downstream insulin-like growth factor (IGF-1) expression, cellular repair signaling, and protein synthesis dynamics.

• Analytical Characterization: Serves as a high-grade reference material for High-Performance Liquid Chromatography (HPLC) and quantitative mass spectrometry workflows.

Technical Specifications

• Compound Name: CJC-1295 No DAC (Modified GRF 1-29)

• CAS Number: 863288-34-0

• Molecular Formula: $\text{C}_{152}\text{H}_{252}\text{N}_{44}\text{O}_{42}$

• Molecular Weight: 3367.97 g/mol

• Purity Grade: $\ge$99% (COA-Verified)

• Physical Form: Lyophilized Powder

• Net Quantity: 5 mg per vial

• Category Focus: Neuroendocrine, Cellular Longevity & Tissue Response Research

Quality Assurance & Laboratory Protocols

Every batch of CJC-1295 No DAC undergoes rigorous third-party analytical validation—including High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS)—to confirm exact sequence identity, molecular uniformity, and purity. Batch-specific Certificates of Analysis (COA) and Safety Data Sheets (SDS) are accessible to support full institutional research compliance.

Storage Instructions: Store unopened lyophilized vials in a dry, dark environment at $-20^\circ\text{C}$. Following initial reconstitution for laboratory workflows, maintain under refrigeration at $2^\circ\text{C}$ to $8^\circ\text{C}$. Refer to the product Safety Data Sheet (SDS) for complete chemical handling guidance.

Research Disclaimer: This product is strictly supplied for in vitro, analytical, and laboratory research purposes only. It is not intended for human or veterinary use, consumption, administration, injection, diagnostic procedures, or therapeutic applications.